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1

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease

Owen A. Ross, Yih-Ru Wu, Mei-Ching Lee, Manabu Funayama, Meng-Ling Chen, Alexandra I. Soto, Ignacio F. Mata, Guey-Jen Lee-Chen, Chiung Mei Chen, Michelle Tang, Yi Zhao, Nobutaka Hattori, Matthew J. Fa

Journal:

Annals of Neurology

Année:

2008

Langue:

english

Fichier:

PDF, 130 KB

english, 2008

2

Analysis of heat-shock protein

Yih-Ru Wu, Cheng-Kuang Wang, Chiung-Mei Chen, Yuying Hsu, Sih-Jing Lin, Yi-Ying Lin, Hon-Chung Fung, Kuo-Hsuan Chang, Guey-Jen Lee-Chen

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 180 KB

english, 2004

3

The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1

Chang, Kuo-Hsuan, Lin, Chih-Hsin, Chen, Hsuan-Chiang, Huang, Hsin-Yu, Chen, Shu-Ling, Lin, Te-Hsien, Ramesh, Chintakunta, Huang, Chin-Chang, Fung, Hon-Chung, Wu, Yih-Ru, Huang, Hei-Jen, Lee-Chen, Guey

Journal:

CNS Neuroscience & Therapeutics

Année:

2016

Langue:

english

Fichier:

PDF, 1004 KB

english, 2016

4

The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice

Chen, Chiung-Mei, Chen, Wan-Ling, Hung, Chen-Ting, Lin, Te-Hsien, Chao, Chih-Ying, Lin, Chih-Hsin, Wu, Yih-Ru, Chang, Kuo-Hsuan, Yao, Ching-Fa, Lee-Chen, Guey-Jen, Su, Ming-Tsan, Hsieh-Li, Hsiu Mei

Journal:

NeuroToxicology

Année:

2018

Langue:

english

Fichier:

PDF, 3.43 MB

english, 2018

5

Tumor necrosis factor-α promoter polymorphism is associated with the risk of Parkinson's disease

Yih-Ru Wu, I-Hsin Feng, Rong-Kuo Lyu, Kuo-Hsuan Chang, Yu-Yun Lin, Huiling Chan, Fen-Ju Hu, Guey-Jen Lee-Chen, Chiung-Mei Chen

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Année:

2007

Langue:

english

Fichier:

PDF, 73 KB

english, 2007

6

Nuclear receptor NR4A2 IVS6 +18insG and brain derived neurotrophic factor (BDNF) V66M polymorphisms and risk of Taiwanese parkinson's disease

Chiung-Mei Chen, I-Cheng Chen, Kuo-Hsuan Chang, Yi-Chun Chen, Rong-Kuo Lyu, Yen-Tzu Liu, Fen-Ju Hu, Chih-Ying Chao, Guey-Jen Lee-Chen, Yih-Ru Wu

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Année:

2007

Langue:

english

Fichier:

PDF, 87 KB

english, 2007

7

Genetic analysis of Parkin in early onset Parkinson's disease (PD): Novel intron 9 g > a single nucleotide polymorphism and risk of Taiwanese PD

Yih-Ru Wu, Chun-Hsien Wu, Chih-Ying Chao, Chun-Chieh Kuan, Wan-Ling Zhang, Cheng-Kuang Wang, Chun-Yuh Chang, Yi-Chun Chang, Guey-Jen Lee-Chen, Chung-Mei Chen

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Année:

2010

Langue:

english

Fichier:

PDF, 147 KB

english, 2010

8

Genetic analysis of “leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1 (LINGO1)” in two independent Chinese parkinson's disease populations

Yih-Ru Wu, Eng-King Tan, Chiung-Mei Chen, Prakash M. Kumar, Guey-Jen Lee-Chen, Sien-Tsong Chen

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Année:

2011

Langue:

english

Fichier:

PDF, 98 KB

english, 2011

9

ATP13A2 variability in Taiwanese Parkinson's disease

Chiung-Mei Chen, Chih-Hsin Lin, Hsueh-Fen Juan, Fen-Ju Hu, Ya-Chin Hsiao, Hsin-Yi Chang, Chih-Ying Chao, I-Cheng Chen, Li-Ching Lee, Tsu-Wei Wang, Ya-Tang Chen, Yi-Tsun Chen, Guey-Jen Lee-Chen, Yih-Ru

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Année:

2011

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2011

10

Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models

Ching-Hsiao Lee, Ching-Fa Yao, Sin-Ming Huang, Shengkai Ko, Yi-Hung Tan, Guey-Jen Lee-Chen, Yi-Ching Wang

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 613 KB

english, 2008

11

Dystonia as a presenting sign of spinocerebellar ataxia type 1

Yih-Ru Wu, Guey-Jen Lee-Chen, Anthony E. Lang, Chiung-Mei Chen, Hsuan-Yuan Lin, Sien-Tsong Chen

Journal:

Movement Disorders

Année:

2004

Langue:

english

Fichier:

PDF, 514 KB

english, 2004

12

Markedly asymmetrical parkinsonism as a leading feature of adult-onset Huntington's disease

Shih-Ching Wang, Guey-Jen Lee-Chen, Cheng-Kung Wang, Chiung-Mei Chen, Lok-Ming Tang, Yih-Ru Wu

Journal:

Movement Disorders

Année:

2004

Langue:

english

Fichier:

PDF, 865 KB

english, 2004

13

Pantothenate kinase-associated neurodegeneration in two Taiwanese siblings: Identification of a novel PANK2 gene mutation

Yih-Ru Wu, Chiung-Mei Chen, Chih-Ying Chao, Ron-Kuo Lyu, Guey-Jen Lee-Chen

Journal:

Movement Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 302 KB

english, 2009

14

An approach for differentiating uniform glutamatergic neurons from mouse embryonic stem cells

Jen-Hua Chuang, Li-Chu Tung, Guey-Jen Lee-Chen, Yi Yin, Yenshou Lin

Journal:

Analytical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 511 KB

english, 2011

15

Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci

I-Cheng Chen, Hsuan-Yuan Lin, Ghin-Chueh Lee, Shih-Huan Kao, Chiung-Mei Chen, Yih-Ru Wu, Hsiu-Mei Hsieh-Li, Ming-Tsan Su, Guey-Jen Lee-Chen

Journal:

BMC Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 3.44 MB

english, 2009

16

Association of TNF-α gene with spontaneous deep intracerebral hemorrhage in the Taiwan population: a case control study

Yi-Chun Chen, Fen-Ju Hu, Phoebe Chen, Yih-Ru Wu, Hsiu-Chuan Wu, Sien-Tsong Chen, Guey-Jen Lee-Chen, Chiung-Mei Chen

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 587 KB

english, 2010

17

Netherton syndrome: mutation analysis of two Taiwanese families

Shuan-Pei Lin, Shu-Yi Huang, Mei-Eng Tu, Yu-Hung Wu, Cheng-Yueh Lin, Hsiang-Yu Lin, Guey-Jen Lee-Chen

Journal:

Archives of Dermatological Research

Année:

2007

Langue:

english

Fichier:

PDF, 332 KB

english, 2007

18

Expression studies of mutations underlying Taiwanese Hunter syndrome (mucopolysaccharidosis type II)

Jui-Hung Chang, Shuan-Pei Lin, Shu-Chuan Lin, Kai-Li Tseng, Chia-Ling Li, Chih-Kuang Chuang, Guey-Jen Lee-Chen

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2005

19

SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications

Yih-Ru Wu, I-Cheng Chen, Bing-Wen Soong, Shih-Huan Kao, Ghin-Chueh Lee, Shu-Yi Huang, Hon-Chung Fung, Guey-Jen Lee-Chen, Chiung-Mei Chen

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 463 KB

english, 2009

20

The CAG repeat in SCA12 functions as aciselement to up-regulate PPP2R2B expression

Chih-Hsin Lin, Chiung-Mei Chen, Yi-Ting Hou, Yih-Ru Wu, Hsiu-Mei Hsieh-Li, Ming-Tsan Su, Guey-Jen Lee-Chen

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 499 KB

english, 2010

21

Renin-angiotensin system polymorphisms in Taiwanese primary vesicoureteral reflux

Kuo-Pao Liu, Ching-Yuang Lin, Han-Jou Chen, Chou-Fu Wei, Guey-Jen Lee-Chen

Journal:

Pediatric Nephrology

Année:

2004

Langue:

english

Fichier:

PDF, 191 KB

english, 2004

22

Mutation identification and characterization of a Taiwanese patient with fucosidosis

Shuan-Pei Lin, Jui-Hung Chang, Maria Paez de la Cadena, Ting-Fang Chang, Guey-Jen Lee-Chen

Journal:

Journal of Human Genetics

Année:

2007

Langue:

english

Fichier:

PDF, 172 KB

english, 2007

23

Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17

Ya-Chin Chang, Cheng-Yueh Lin, Chen-Ming Hsu, Hsin-Chieh Lin, Yu-Hsiang Chen, Guey-Jen Lee-Chen, Ming-Tsan Su, Long-Sun Ro, Chiung-Mei Chen, Hsiu Mei Hsieh-Li

Journal:

Journal of Neurochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2011

24

Significance of the tissue kallikrein promoter and transforming growth factor-beta1 polymorphisms with renal progression in children with vesicoureteral reflux

Lee-Chen, Guey-Jen, Liu, Kuo-Pao, Lai, Yi-Chun, Juang, Huei-Shiuan, Huang, Shu-Yi, Lin, Ching-Yuang

Journal:

Kidney International

Année:

2004

Langue:

english

Fichier:

PDF, 111 KB

english, 2004

25

Vaccinia virus gene D12L encodes the small subunit of the viral mRNA capping enzyme

Edward G. Niles, Guey-Jen Lee-Chen, Stewart Shuman, Bernard Moss, Steven S. Broyles

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1989

26

SCA8 mRNA expression suggests an antisense regulation of KLHL1 and correlates to SCA8 pathology

Wei-Lun Chen, Jun-Wei Lin, Hei-Jen Huang, Su-Min Wang, Ming-Tsan Su, Guey-Jen Lee-Chen, Chiung-Mei Chen, Hsiu Mei Hsieh-Li

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 950 KB

english, 2008

27

Map positions of the 5′ ends of eight mrnas synthesized from the late genes in the vaccinia virus HindIII D fragment

Guey-Jen Lee-Chen, Edward G. Niles

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 6.55 MB

english, 1988

28

Transcription and translation mapping of the 13 genes in the vaccinia virus Hindlll D fragment

Guey-Jen Lee-Chen, Edward G. Niles

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 3.06 MB

english, 1988

29

Structure of the transcription initiation and termination sequences of seven early genes in the vaccinia virus HindIII D fragment

Guey-Jen Lee-Chen, Nancy Bourgeois, Kirk Davidson, Richard C. Condit, Edward G. Niles

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 6.14 MB

english, 1988

30

Detection of hunter syndrome (mucopolysaccharidosis type II) in Taiwanese: Biochemical and linkage studies of the iduronate-2-sulfatase gene defects in MPS II patients and carriers

Shuan-Pei Lin, Jui-Hung Chang, Guey-Jen Lee-Chen, Dar-Shong Lin, Hsiang-Yu Lin, Chih-Kuang Chuang

Journal:

Clinica Chimica Acta

Année:

2006

Langue:

english

Fichier:

PDF, 160 KB

english, 2006

31

Characterization of a novel p.S305P and a known c.1006 +5G > C splice site mutation in human iduronate-2-sulfatase associated with mucopolysaccharidosis type II

Jui-Hung Chang, Shuan-Pei Lin, Chih-Kuang Chuang, Guey-Jen Lee-Chen

Journal:

Clinica Chimica Acta

Année:

2007

Langue:

english

Fichier:

PDF, 209 KB

english, 2007

32

Analyses of interaction effect between apolipoprotein E polymorphism and alcohol use as well as cholesterol concentrations on spontaneous deep intracerebral hemorrhage in the Taiwan population

Yi-Chun Chen, Guey-Jen Lee-Chen, Yih-Ru Wu, Fen-Ju Hu, Hsiu-Chuan Wu, Hung-Chou Kuo, Chun-Che Chu, Shan-Jin Ryu, Sien-Tsong Chen, Chiung-Mei Chen

Journal:

Clinica Chimica Acta

Année:

2009

Langue:

english

Fichier:

PDF, 140 KB

english, 2009

33

SCA17 repeat expansion: Mildly expanded CAG/CAA repeat alleles in neurological disorders and the functional implications

Chiung-Mei Chen, Li-Ching Lee, Bing-Wen Soong, Hon-Chung Fung, Wen-Chuin Hsu, Pei-Ying Lin, Hui-Ju Huang, Fen-Lin Chen, Cheng-Yueh Lin, Guey-Jen Lee-Chen, Yih-Ru Wu

Journal:

Clinica Chimica Acta

Année:

2010

Langue:

english

Fichier:

PDF, 650 KB

english, 2010

34

Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson's disease among Taiwanese

Yih-Ru Wu, Chiung-Mei Chen, Yi-Chun Chen, Chih-Ying Chao, Long Sun Ro, Hon-Chung Fung, Ya-Chin Hsiao, Fen-Ju Hu, Guey-Jen Lee-Chen

Journal:

Clinica Chimica Acta

Année:

2010

Langue:

english

Fichier:

PDF, 155 KB

english, 2010

35

Analysis of the PINK1 gene in a cohort of patients with sporadic early-onset parkinsonism in Taiwan

Hon-Chung Fung, Chiung-Mei Chen, John Hardy, Andrew B. Singleton, Guey-Jen Lee-Chen, Yih-Ru Wu

Journal:

Neuroscience Letters

Année:

2006

Langue:

english

Fichier:

PDF, 82 KB

english, 2006

36

HSPA5 promoter polymorphisms and risk of Parkinson's disease in Taiwan

Chiung-Mei Chen, Yih-Ru Wu, Fen-Ju Hu, Yi-Chun Chen, Tzu-Jung Chuang, Ya-Fen Cheng, Guey-Jen Lee-Chen

Journal:

Neuroscience Letters

Année:

2008

Langue:

english

Fichier:

PDF, 100 KB

english, 2008

37

The SCA17 phenotype can include features of MSA-C, PSP and cognitive impairment

I-Sheng Lin, Ruey-Meei Wu, Guey-Jen Lee-Chen, Din-E Shan, Katrina Gwinn-Hardy

Journal:

Parkinsonism & Related Disorders

Année:

2007

Langue:

english

Fichier:

PDF, 341 KB

english, 2007

38

Genetic analysis of HLA-DRA region variation in Taiwanese Parkinson’s disease

Han-Lin Chiang, Guey-Jen Lee-Chen, Chiung Mei Chen, Yi-Chun Chen, Chei-Mei Lee, Ming-Hui Liao, Yih-Ru Wu

Journal:

Parkinsonism & Related Disorders

Année:

2012

Langue:

english

Fichier:

PDF, 121 KB

english, 2012

39

Recurrent cerebral venous thrombosis: An Arg359X mutation in the antithrombin gene in a Taiwanese family

Chiung-Mei Chen, Guey-Jen Lee-Chen, Yih-Ru Wu, Cheng-Yueh Lin, Chi-Jen Chen, I-Cheng Chen, Long-Sun Ro

Journal:

Thrombosis Research

Année:

2006

Langue:

english

Fichier:

PDF, 188 KB

english, 2006

40

Protein kinase Cη polymorphism and the susceptibilities to intracerebral hemorrhage in the Taiwan population

Yi-Chun Chen, Phoebe Chen, Yih-Ru Wu, Shian-Sen Shie, Sien-Tsong Chen, Guey-Jen Lee-Chen, Chiung-Mei Chen

Journal:

Neuroscience Letters

Année:

2012

Langue:

english

Fichier:

PDF, 184 KB

english, 2012

41

Study of a Taiwanese family with oculopharyngeal muscular dystrophy

Hung-Chou Kuo, Chiung-Mei Chen, Guey-Jen Lee-Chen, Fen-Ju Hu, Chun-Che Chu, Chia-Wei Liou, Chin-Chang Huang

Journal:

Journal of the Neurological Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 219 KB

english, 2009

42

Familial defective apolipoprotein B-100: detection and haplotype analysis of the Arg3500→Gln mutation in hyperlipidemic Chinese

Yen-Ni Teng, Ju-Pin Pan, Shiu-Ching Chou, Der-Yan Tai, Guey-Jen Lee-Chen

Journal:

Atherosclerosis

Année:

2000

Langue:

english

Fichier:

PDF, 129 KB

english, 2000

43

Downregulation of proteins involved in the endoplasmic reticulum stress response and Nrf2-ARE signaling in lymphoblastoid cells of spinocerebellar ataxia type 17

Lee, Li-Ching, Weng, Yu-Ting, Wu, Yih-Ru, Soong, Bing-Wen, Tseng, Yung-Che, Chen, Chiung-Mei, Lee-Chen, Guey-Jen

Journal:

Journal of Neural Transmission

Année:

2014

Langue:

english

Fichier:

PDF, 575 KB

english, 2014

44

HTRA2variations in Taiwanese Parkinson’s disease

Chen, Chiung-Mei, Wu, Chun-Hsien, Hsieh, Chin-Hsia, Lin, Chih-Hsin, Chen, I-Cheng, Chen, Yi-Chun, Lee, Li-Ching, Lee, Chi-Mei, Tseng, Yung-Che, Lee-Chen, Guey-Jen, Wu, Yih-Ru

Journal:

Journal of Neural Transmission

Année:

2014

Langue:

english

Fichier:

PDF, 472 KB

english, 2014

45

Effect of statin treatment on adrenomyeloneuropathy with cerebral inflammation: A revisit

Shih, Chen-Chang, Wu, Yih-Ru, Lee-Chen, Guey-Jen, Chao, Chih-Ying

Journal:

Clinical Neurology and Neurosurgery

Année:

2013

Langue:

english

Fichier:

PDF, 717 KB

english, 2013

46

Association between PARK16 and Parkinson's disease in the Han Chinese population: a meta-analysis

Chang, Kuo-Hsuan, Chen, Chiung-Mei, Chen, Yi-Chun, Lyu, Rong-Kuo, Chang, Hong-Shiu, Ro, Long-Sun, Lee-Chen, Guey-Jen, Wu, Yih-Ru

Journal:

Neurobiology of Aging

Année:

2013

Langue:

english

Fichier:

PDF, 222 KB

english, 2013

47

Imaging and therapy of human malignant gliomas utilising the monoclonal antibody MUC 2–63

Chang, Kuo-Hsuan, Chen, Chiung-Mei, Chen, Yi-Chun, Lyu, Rong-Kuo, Chang, Hong-Shiu, Ro, Long-Sun, Lee-Chen, Guey-Jen, Wu, Yih-Ru

Journal:

European Journal of Cancer and Clinical Oncology

Année:

1990

Langue:

english

Fichier:

PDF, 191 KB

english, 1990

48

Genetic analysis of NFE2L2 promoter variation in Taiwanese Parkinson's disease

Chen, Yi-Chun, Wu, Yih-Ru, Wu, Yi-Ci, Lee-Chen, Guey-Jen, Chen, Chiung-Mei

Journal:

Parkinsonism & Related Disorders

Année:

2013

Langue:

english

Fichier:

PDF, 128 KB

english, 2013

49

Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3

Chang, Kuo-Hsuan, Chen, Wan-Ling, Wu, Yih-Ru, Lin, Te-Hsien, Wu, Yi-Ci, Chao, Chih-Ying, Lin, Jung-Yaw, Lee, Li-Ching, Chen, Yi-Chun, Lee-Chen, Guey-Jen, Chen, Chiung-Mei

Journal:

Neuropharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2014

50

Variant R244H in Na+/Mg2+ exchanger SLC41A1 in Taiwanese Parkinson's disease is associated with loss of Mg2+ efflux function

Lin, Chih-Hsin, Wu, Yih-Ru, Chen, Wan-Ling, Wang, Hao-Chun, Lee, Chi-Mei, Lee-Chen, Guey-Jen, Chen, Chiung-Mei

Journal:

Parkinsonism & Related Disorders

Année:

2014

Langue:

english

Fichier:

PDF, 662 KB

english, 2014